5-Hydroxymethyldeoxyuridine

Cas：5116-24-5

Product Information：

5-Hydroxymethyldeoxyuridine is a nucleoside analog with anticancer and antiviral activities. It inhibits the replication of murine S180 lung carcinoma cells and Ehrlich ascites mammary carcinoma cells (ED50s = 8.5 and 4 μM, respectively) and multiple human leukemia cell lines (IC50s = 1.7-5.8 μM).

Chemical Formula: C10H14N2O6

Exact Mass: 258.0852

Molecular Weight: 258.23

Elemental Analysis: C, 46.51; H, 5.46; N, 10.85; O, 37.17

Synonym: 

• Hydroxymethyldeoxyuridine

α-Hydroxythymidine

2'-Deoxy-5-(hydroxymethyl)uridine

5-Hydroxymethyl-2'-deoxyuridine

Chemical Name: 

Uridine, 2'-deoxy-5-(hydroxymethyl)

InChi Key: 

IPAVKOYJGUMINP-XLPZGREQSA-N

InChi Code: InChI=1S/C10H14N2O6/c13-3-5-2-12(10(17)11-9(5)16)8-1-6(15)7(4-14)18-8/h2,6-8,13-15H,1,3-4H2,(H,11,16,17)/t6-,7+,8+/m0/s1

Smiles Code:

OC[C@@H]1[C@H](C[C@H](N2C(NC(C(CO)=C2)=O)=O)O1)O

Technical Data：

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Products are for research use only. Not for human use.