FOY-251 mesylate

Cas：71079-09-9

Product Information：

FOY-251 is a metabolite of Camostat that acts as a pollen protease inhibitor for prevention and control of allergies.

Chemical Formula: C17H19N3O7S

Exact Mass: 409.0944

Molecular Weight: 409.41

Elemental Analysis: C, 49.87; H, 4.68; N, 10.26; O, 27.35; S, 7.83

Synonym:

FOY 251

FOY251

FOY-251

FOY-251 mesylate

Chemical Name:

4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]-benzeneacetic Acid Monomethanesulfonate

InChi Key:

JXMOPIDYHUYOED-UHFFFAOYSA-N

InChi Code: InChI=1S/C16H15N3O4.CH4O3S/c17-16(18)19-12-5-3-11(4-6-12)15(22)23-13-7-1-10(2-8-13)9-14(20)21;1-5(2,3)4/h1-8H,9H2,(H,20,21)(H4,17,18,19);1H3,(H,2,3,4)

Smiles Code:

O=C(O)CC1=CC=C(OC(C2=CC=C(NC(N)=N)C=C2)=O)C=C1.CS(=O)(O)=O

Technical Data：

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

In Vitro：

FOY-251 represents a dose-dependent inhibition of equivalent current in M-1 cells.

FOY-251 inhibits the proteolytic activity of prostasin.

References：

1. Beckh K, Weidenbach H, Weidenbach F, Müller R, Adler G. Hepatic and pancreatic metabolism and biliary excretion of the protease inhibitor camostat mesilate. Int J Pancreatol. 1991;10(3-4):197-205. doi:10.1007/BF02924157

Products are for research use only. Not for human use.