FOY-251 mesylate

FOY-251 is a metabolite of Camostat that acts as a pollen protease inhibitor for prevention and control of allergies.

Product information

CAS Number: 71079-09-9

Molecular Weight: 409.41

Formula: C17H19N3O7S

Synonym:

FOY-251

FOY 251

FOY251

FOY-251 mesylate

Chemical Name: 4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]-benzeneacetic Acid Monomethanesulfonate

Smiles: CS(O)(=O)=O.NN=CNC1C=CC(=CC=1)C(=O)OC1C=CC(CC(O)=O)=CC=1

InChiKey: DQBRVWBDBFFGEU-UHFFFAOYSA-N

InChi: InChI=1S/C16H15N3O4.CH4O3S/c17-19-10-18-13-5-3-12(4-6-13)16(22)23-14-7-1-11(2-8-14)9-15(20)21;1-5(2,3)4/h1-8,10H,9,17H2,(H,18,19)(H,20,21);1H3,(H,2,3,4)

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

How to use

In Vitro:

FOY-251 represents a dose-dependent inhibition of equivalent current in M-1 cells. FOY-251 inhibits the proteolytic activity of prostasin.

References:

1. Beckh K, Weidenbach H, Weidenbach F, Müller R, Adler G. Hepatic and pancreatic metabolism and biliary excretion of the protease inhibitor camostat mesilate. Int J Pancreatol. 1991;10(3-4):197-205. doi:10.1007/BF02924157

Products are for research use only. Not for human use.