Description
Cas:71079-09-9
Product Information:
FOY-251 is a metabolite of Camostat that acts as a pollen protease inhibitor for prevention and control of allergies.
Chemical Formula: C17H19N3O7S
Exact Mass: 409.0944
Molecular Weight: 409.41
Elemental Analysis: C, 49.87; H, 4.68; N, 10.26; O, 27.35; S, 7.83
Synonym:
FOY 251
FOY251
FOY-251
FOY-251 mesylate
Chemical Name:
4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]-benzeneacetic Acid Monomethanesulfonate
InChi Key:
JXMOPIDYHUYOED-UHFFFAOYSA-N
InChi Code: InChI=1S/C16H15N3O4.CH4O3S/c17-16(18)19-12-5-3-11(4-6-12)15(22)23-13-7-1-10(2-8-13)9-14(20)21;1-5(2,3)4/h1-8H,9H2,(H,20,21)(H4,17,18,19);1H3,(H,2,3,4)
Smiles Code:
O=C(O)CC1=CC=C(OC(C2=CC=C(NC(N)=N)C=C2)=O)C=C1.CS(=O)(O)=O
Technical Data:
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
In Vitro:
FOY-251 represents a dose-dependent inhibition of equivalent current in M-1 cells.
FOY-251 inhibits the proteolytic activity of prostasin.
References:
-
Beckh K, Weidenbach H, Weidenbach F, Müller R, Adler G. Hepatic and pancreatic metabolism and biliary excretion of the protease inhibitor camostat mesilate. Int J Pancreatol. 1991;10(3-4):197-205. doi:10.1007/BF02924157
Products are for research use only. Not for human use.
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