OUN20985

Cas：2244520-98-5

Product Information：

OUN20985, also known as Homo-PROTAC cereblon degrader 1, is a cereblon degrader. OUN20985 has CAS#2244520-98-5, no formal name For the convenience of scientific communication, we named it as OUN20985 (combined from Inchi key plus CAS#) according to Hodoodo Chemical Nomenclature.

Chemical Formula: C32H32N6O10

Exact Mass: 660.218

Molecular Weight: 660.64

Elemental Analysis: C, 58.18; H, 4.88; N, 12.72; O, 24.22

Synonym:

Homo-PROTAC cereblon degrader 1

OUN20985

OUN-20985

OUN 20985

Chemical Name: 4,4'-(((ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl))bis(azanediyl))bis(2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione)

InChi Key: 

OXIPFLHBDVDLDS-UHFFFAOYSA-N

InChi Code: InChI=1S/C32H32N6O10/c39-23-9-7-21(27(41)35-23)37-29(43)17-3-1-5-19(25(17)31(37)45)33-11-13-47-15-16-48-14-12-34-20-6-2-4-18-26(20)32(46)38(30(18)44)22-8-10-24(40)36-28(22)42/h1-6,21-22,33-34H,7-16H2,(H,35,39,41)(H,36,40,42)

Smiles Code:

O=C(N1C2CCC(NC2=O)=O)C3=CC=CC(NCCOCCOCCNC4=C5C(C(N(C6CCC(NC6=O)=O)C5=O)=O)=CC=C4)=C3C1=O

Technical Data：

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

References：

1. Steinebach C, et al. Homo-PROTACs for the Chemical Knockdown of Cereblon. ACS Chem Biol. 2018 Sep 21;13(9):2771-2782.

Products are for research use only. Not for human use.