Description
Cas:431996-53-1
Product Information:
Filastatin is a nontoxic inhibitor of adhesion to human cells, and it affects multiple Candida species. Filastatin blocks the ability of Candida albicans, and other Candida sp. to bind to polystyrene, and human A549 cell monolayers. Filastatin also blocks biofilm formation and yeast-to-hyphal morphologic transition through inhibition of the hyphal-specific promoter HWP1.
Chemical Formula: C18H18ClN3O3
Exact Mass: 359.1037
Molecular Weight: 359.81
Elemental Analysis: C, 60.09; H, 5.04; Cl, 9.85; N, 11.68; O, 13.34
Synonym:
431996-53-1
C18H18ClN3O3
Oprea1_751412
SCHEMBL15506294
AOB4963
SYN5098
EX-A4056
ZINC4758640
STL420152
AKOS003304760
MCULE-6735757823
NCGC00402261-03
AS-16462
HY-124701
CS-0087356
Z57715689
1-(3-chloro-4-methylbenzoyl)-4-(4-nitrophenyl)piperazine
Chemical Name: (3-Chloro-4-methyl-phenyl)-[4-(4-nitro-phenyl)-piperazin-1-yl]-methanone
InChi Key:
PNECWWUOUHGWQG-UHFFFAOYSA-N
InChi Code: InChI=1S/C18H18ClN3O3/c1-13-2-3-14(12-17(13)19)18(23)21-10-8-20(9-11-21)15-4-6-16(7-5-15)22(24)25/h2-7,12H,8-11H2,1H3
Smiles Code:
O=C(C1=CC=C(C)C(Cl)=C1)N2CCN(C3=CC=C([N+]([O-])=O)C=C3)CC2
Technical Data:
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
References:
-
Ahmed Fazly, et al. Chemical screening identifies filastatin, a small molecule inhibitor of Candida albicans adhesion, morphogenesis, and pathogenesis. Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13594-9.
Products are for research use only. Not for human use.
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