Filastatin


Catalog No. size PriceQuantity
M7074-2 2mg solid $100
M7074-3 10mg solid $401

Description

Filastatin is a nontoxic inhibitor of adhesion to human cells, and it affects multiple Candida species. Filastatin blocks the ability of Candida albicans, and other Candida sp. to bind to polystyrene, and human A549 cell monolayers. Filastatin also blocks biofilm formation and yeast-to-hyphal morphologic transition through inhibition of the hyphal-specific promoter HWP1.

Product information

CAS Number: 431996-53-1

Molecular Weight: 359.81

Formula: C18H18ClN3O3

Synonym:

AS-16462

HY-124701

431996-53-1

C18H18ClN3O3

Oprea1_751412

SCHEMBL15506294

AOB4963

SYN5098

EX-A4056

ZINC4758640

STL420152

AKOS003304760

MCULE-6735757823

NCGC00402261-03

CS-0087356

Z57715689

1-(3-chloro-4-methylbenzoyl)-4-(4-nitrophenyl)piperazine

Chemical Name: (3-Chloro-4-methyl-phenyl)-[4-(4-nitro-phenyl)-piperazin-1-yl]-methanone

Smiles: CC1=CC=C(C=C1Cl)C(=O)N1CCN(CC1)C1C=CC(=CC=1)[N+]([O-])=O

InChiKey: PNECWWUOUHGWQG-UHFFFAOYSA-N

InChi: InChI=1S/C18H18ClN3O3/c1-13-2-3-14(12-17(13)19)18(23)21-10-8-20(9-11-21)15-4-6-16(7-5-15)22(24)25/h2-7,12H,8-11H2,1H3

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

References:

  1. Ahmed Fazly, et al. Chemical screening identifies filastatin, a small molecule inhibitor of Candida albicans adhesion, morphogenesis, and pathogenesis. Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13594-9.

Products are for research use only. Not for human use.

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