Catalog No. size PriceQuantity
M7099-2 2mg solid $141
M7099-10 10mg solid $570



Product Information

DUN71755, also known as nAChR agonist 1, is a potent, brain-permeable, and orally efficacious positive allosteric modulator of α7 nicotinic acetylcholine receptor (α7 nAChR). DUN71755 is reported in WO 2012114285. DUN71755 has CAS#1394371-75-5, no formal name. For the convenience of scientific communication, we named it as DUN71755 (combined from Inchi key plus CAS#) according to Hodoodo Chemical Nomenclature.


Chemical Formula: C20H18ClNO3S2


Exact Mass: 419.0417


Molecular Weight: 419.938


Elemental Analysis: C, 57.20; H, 4.32; Cl, 8.44; N, 3.34; O, 11.43; S, 15.27




nAChR agonist 1


DUN 71755



Chemical Name: 4-(5-(4-chlorophenyl)-4-methyl-2-propionylthiophen-3-yl)benzenesulfonamide


InChi Key: 



InChi Code: InChI=1S/C20H18ClNO3S2/c1-3-17(23)20-18(13-6-10-16(11-7-13)27(22,24)25)12(2)19(26-20)14-4-8-15(21)9-5-14/h4-11H,3H2,1-2H3,(H2,22,24,25)


Smiles Code:




Technical Data:


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001





  1. Sinha N, et al.Discovery of Novel, Potent, Brain-Permeable, and Orally Efficacious Positive Allosteric Modulator of α7 Nicotinic Acetylcholine Receptor [4-(5-(4-Chlorophenyl)-4-methyl-2-propionylthiophen-3-yl)benzenesulfonamide]: Structure-Activity Relationship and Preclinical Characterization. J Med Chem. 2020 Feb 13;63(3):944-960.


Products are for research use only. Not for human use.

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