CCRP2

CCRP2, also known as TLX agonist 1 and SUN23314, is an orphan nuclear receptor tailless (TLX, NR2E1) modulator (EC50=1μM; Kd= 650 nM). TLX agonist 1 potentiates TLX transcriptional repressive activity. CCRP2 was reported in PLoS One . 2014 Jun 17;9(6):e99440.

Product information

CAS Number: 958323-31-4

Molecular Weight: 374.48

Formula: C23H26N4O

Synonym:

SUN-23314

CCRP-2

TLX agonist 1

SUN23314

SUN 23314

CCRP2

CCRP 2

Chemical Name: (4-benzhydrylpiperazin-1-yl)(1,5-dimethyl-1H-pyrazol-3-yl)methanone

Smiles: CN1N=C(C=C1C)C(=O)N1CCN(CC1)C(C1C=CC=CC=1)C1C=CC=CC=1

InChiKey: SSGJAUSSGPIZEE-UHFFFAOYSA-N

InChi: InChI=1S/C23H26N4O/c1-18-17-21(24-25(18)2)23(28)27-15-13-26(14-16-27)22(19-9-5-3-6-10-19)20-11-7-4-8-12-20/h3-12,17,22H,13-16H2,1-2H3

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

References:

1. Benod C, Villagomez R, Filgueira CS, et al. The human orphan nuclear receptor tailless (TLX, NR2E1) is druggable. PLoS One. 2014;9(6):e99440. Published 2014 Jun 17. doi:10.1371/journal.pone.0099440

Products are for research use only. Not for human use.