DUN73423


Catalog No. size PriceQuantity
M7115-2 2mg solid $120
M7115-10 10mg solid $488

Description

DUN73423 is a RET/KDR-Selective Inhibitor of RETV804M Kinase with IC50 = 7 nM. DUN73423 was listed in ACS Med Chem Lett . 2020 Feb 28;11(4):497-505 (compound 5).

Product information

CAS Number: 2414373-42-3

Molecular Weight: 344.37

Formula: C19H16N6O

Synonym:

DUN-73423

DUN73423

DUN 73423

Chemical Name: DUN73423

Smiles: NC(=O)C1C=CC(=CC=1)C1C=NN2C=CC(NCC3C=CN=CC=3)=NC2=1

InChiKey: DICBAYNNPUCOOQ-UHFFFAOYSA-N

InChi: InChI=1S/C19H16N6O/c20-18(26)15-3-1-14(2-4-15)16-12-23-25-10-7-17(24-19(16)25)22-11-13-5-8-21-9-6-13/h1-10,12H,11H2,(H2,20,26)(H,22,24)

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DUN-73423

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

References:

  1. Newton R, Waszkowycz B, Seewooruthun C, et al. Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RETV804M Kinase. ACS Med Chem Lett. 2020;11(4):497-505. Published 2020 Feb 28. doi:10.1021/acsmedchemlett.9b00615

Products are for research use only. Not for human use.

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