BC-DXI-843 is AIMP2-DX2 inhibitor. It as a promising lead for development of novel therapeutics targeting AIMP2-DX2 in lung cancer.
CAS Number: 2421117-98-6
Molecular Weight: 546.66
Chemical Name: (S)-3-(1H-Indol-3-yl)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-2-(4-methylphenylsulfonamido)propanamide
Appearance: Solid Power.
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined.
HS Tariff Code: 382200
- Aneesh Sivaraman, Dae Gyu Kim, Deepak Bhattarai, Minkyoung Kim, Hwa Young Lee, Semi Lim, Jiwon Kong, Ja-il GooSeunghwan Shim, Seungbeom Lee, Young-Ger Suh,Yongseok Choi, Sunghoon Kim, Kyeong Lee. Synthesis and Structure–Activity Relationships of Arylsulfonamides as AIMP2-DX2 Inhibitors for the Development of a Novel Anticancer Therapy. J. Med. Chem. 2020. doi: 10.1021/acs.jmedchem.9b01961.
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