Description
Abametapir is the active ingredient of Xeglyze Lotion. Abametapir inhibits metalloproteinases; enzymes that are essential to physiological processes critical for egg development and the survival of nymph and adult lice. In vitro and ex vivo research has demonstrated that abametapir not only kills the lice, but also prevents hatching of their eggs. Xeglyze Lotion is emerging as a differentiated development candidate to treat head lice infestations.
Product information
CAS Number: 1762-34-1
Molecular Weight: 184.24
Formula: C12H12N2
Synonym:
HA-44
BRN-0123183
Xeglyze
HA44
HA 44
BRN 0123183
BRN0123183
6,6'-Bi-3-picoline
Chemical Name: 5,5'-dimethyl-2,2'-bipyridinyl
Smiles: CC1C=NC(=CC=1)C1C=CC(C)=CN=1
InChiKey: PTRATZCAGVBFIQ-UHFFFAOYSA-N
InChi: InChI=1S/C12H12N2/c1-9-3-5-11(13-7-9)12-6-4-10(2)8-14-12/h3-8H,1-2H3
Technical Data
Appearance: Solid Power.
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO, not in water
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined.
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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