Abametapir

Cas：1762-34-1

Product Information：

Abametapir is the active ingredient of Xeglyze Lotion. Abametapir inhibits metalloproteinases; enzymes that are essential to physiological processes critical for egg development and the survival of nymph and adult lice. In vitro and ex vivo research has demonstrated that abametapir not only kills the lice, but also prevents hatching of their eggs. Xeglyze Lotion is emerging as a differentiated development candidate to treat head lice infestations.

Chemical Formula: C12H12N2

Exact Mass: 184.1

Molecular Weight: 184.242

Elemental Analysis: C, 78.23; H, 6.57; N, 15.21

Synonym: 

HA-44

HA44

HA 44

BRN 0123183

BRN-0123183

BRN0123183

Xeglyze

6,6'-Bi-3-picoline

Chemical Name: 

5,5'-dimethyl-2,2'-bipyridinyl

InChi Key:

PTRATZCAGVBFIQ-UHFFFAOYSA-N

InChi Code: InChI=1S/C12H12N2/c1-9-3-5-11(13-7-9)12-6-4-10(2)8-14-12/h3-8H,1-2H3

Smiles Code:

CC1=CN=C(C2=NC=C(C)C=C2)C=C1

Technical Data：

Appearance: White to off-white solidw powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Products are for research use only. Not for human use.