VH 032 amide-PEG5-acid


Catalog No. size PriceQuantity
M7142-2 2mg solid $75
M7142-10 10mg solid $316

Description

VH 032 amide-PEG5-acid is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC® research and development. It incorporates an E3 ligase ligand plus a PEG5 linker with terminal carboxylic acid ready for conjugation to a target protein ligand. It is part of a range of functionalized tool molecules for PROTAC R&D.

Product information

CAS Number: 2172820-14-1

Molecular Weight: 750.90

Formula: C36H54N4O11S

Synonym:

E3 Ligase Ligand-Linker Conjugates 58

BCP33436

(S,R,S)-AHPC-PEG5-COOH

2172820-14-1

SCHEMBL19786337

EX-A3940

HY-130271

CS-0106354

VH032-PEG5-COOH

VHL Ligand-Linker Conjugates 16

[2-[2-[2-[2-[3-[[(2S)-1-[(2S,4R)-4-hydroxy-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

Chemical Name: [2-[2-[2-[2-[3-[[(2S)-1-[(2S,4R)-4-hydroxy-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]amino]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

Smiles: CC1N=CSC=1C1C=CC(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCOCCOCCOC(C)C(O)=O)C(C)(C)C)=CC=1

InChiKey: KEVFVBURAAZURM-ZAPNVNOBSA-N

InChi: InChI=1S/C36H54N4O11S/c1-24-31(52-23-38-24)27-8-6-26(7-9-27)21-37-33(43)29-20-28(41)22-40(29)34(44)32(36(3,4)5)39-30(42)10-11-47-12-13-48-14-15-49-16-17-50-18-19-51-25(2)35(45)46/h6-9,23,25,28-29,32,41H,10-22H2,1-5H3,(H,37,43)(H,39,42)(H,45,46)/t25?,28-,29+,32-/m1/s1

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

Products are for research use only. Not for human use.

Payment & Security

American Express Diners Club Discover JCB Mastercard PayPal Venmo Visa

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed