Ethyl LipotF


Catalog No. size PriceQuantity
M7167-2 2mg solid $100
M7167-10 10mg solid $406

Description

Cas:1808089-27-1

Product Information:

Ethyl LipotF is a selective FTO inhibitor.

 

Chemical Formula: C19H19N3O4

 

Exact Mass: 353.1376

 

Molecular Weight: 353.378

 

Elemental Analysis: C, 64.58; H, 5.42; N, 11.89; O, 18.11

 

Synonym:

 

Ethyl LipotF

Ethyl-LipotF

Ethyl LipotF

 

Chemical Name:

ethyl (E)-4-(2-(4-benzylnicotinoyl)hydrazinyl)-4-oxobut-2-enoate

 

InChi Key:

XUKLGMSFWAEOPR-CMDGGOBGSA-N

 

InChi Code: InChI=1S/C19H19N3O4/c1-2-26-18(24)9-8-17(23)21-22-19(25)16-13-20-11-10-15(16)12-14-6-4-3-5-7-14/h3-11,13H,2,12H2,1H3,(H,21,23)(H,22,25)/b9-8+

 

Smiles Code:

O=C(C1=C(C=CN=C1)CC2=CC=CC=C2)NNC(/C=C/C(OCC)=O)=O

 

 

Technical Data:

 

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

 

 

References

 

  1. Toh et al (2015) A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor of N6-methyladenosine demethylase FTO. Chem.Sci. 6 112 PMID: 28553460

 

  1. Cheong et al (2018) A fluorescent methylation-switchable probe for highly sensitive analysis of FTO N6-methyladenosine demethylase activity in cells. Chem.Sci. 9 7174 PMID: 30288236

 

Products are for research use only. Not for human use.

 

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