Ethyl LipotF

Ethyl LipotF is a selective FTO inhibitor.

Product information

CAS Number: 1808089-27-1

Molecular Weight: 353.37

Formula: C19H19N3O4

Synonym:

Ethyl-LipotF

Ethyl LipotF

Ethyl LipotF

Chemical Name: ethyl (E)-4-(2-(4-benzylnicotinoyl)hydrazinyl)-4-oxobut-2-enoate

Smiles: CCOC(=O)/C=C/C(=O)NNC(=O)C1=CN=CC=C1CC1C=CC=CC=1

InChiKey: XUKLGMSFWAEOPR-CMDGGOBGSA-N

InChi: InChI=1S/C19H19N3O4/c1-2-26-18(24)9-8-17(23)21-22-19(25)16-13-20-11-10-15(16)12-14-6-4-3-5-7-14/h3-11,13H,2,12H2,1H3,(H,21,23)(H,22,25)/b9-8+

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

References:

1. Toh et al (2015) A strategy based on nucleotide specificity leads to a subfamily-selective and cell-active inhibitor of N6-methyladenosine demethylase FTO. Chem.Sci. 6 112 PMID: 28553460
2. Cheong et al (2018) A fluorescent methylation-switchable probe for highly sensitive analysis of FTO N6-methyladenosine demethylase activity in cells. Chem.Sci. 9 7174 PMID: 30288236

Products are for research use only. Not for human use.