Santacruzamate A


Catalog No. size PriceQuantity
M7169-2 2mg solid $105
M7169-10 10mg solid $441

Description

Santacruzamate A, is a potent and selective histone deacetylase inhibitor from the Panamanian marine cyanobacterium cf. Symploca sp. CAY10683 inhibits HDAC2 and HDAC6 with IC50 values of 0.119 and 434 nM, respectively.

Product information

CAS Number: 1477949-42-0

Molecular Weight: 278.35

Formula: C15H22N2O3

Synonym:

CAY-10683

CAY10683

CAY 10683

Santacruzamate A

Chemical Name: ethyl (4-oxo-4-(phenethylamino)butyl)carbamate

Smiles: CCOC(=O)NCCCC(=O)NCCC1C=CC=CC=1

InChiKey: HTOYBIILVCHURC-UHFFFAOYSA-N

InChi: InChI=1S/C15H22N2O3/c1-2-20-15(19)17-11-6-9-14(18)16-12-10-13-7-4-3-5-8-13/h3-5,7-8H,2,6,9-12H2,1H3,(H,16,18)(H,17,19)

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO, not in water

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

References:

  1. Pavlik et al (2013) Santacruzamate A, a potent and selective histone deacetylase inhibitor from the Panamanian marine cyanobacterium cf. Symploca sp. J.Nat.Prod. 76 2026 PMID: 24164245
  2. Gordon et al (2020) A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature. 583 459 PMID: 32353859

Products are for research use only. Not for human use.

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