Santacruzamate A


Catalog No. size PriceQuantity
M7169-2 2mg solid $105
M7169-10 10mg solid $441

Description

Cas:1477949-42-0

Product Information:

Santacruzamate A, is a potent and selective histone deacetylase inhibitor from the Panamanian marine cyanobacterium cf. Symploca sp. CAY10683 inhibits HDAC2 and HDAC6 with IC50 values of 0.119 and 434 nM, respectively.

 

Chemical Formula: C15H22N2O3

 

Exact Mass: 278.163

 

Molecular Weight: 278.352

 

Elemental Analysis: C, 64.73; H, 7.97; N, 10.06; O, 17.24

 

Synonym:

 

CAY10683

CAY-10683

CAY 10683

Santacruzamate A

 

Chemical Name: 

ethyl (4-oxo-4-(phenethylamino)butyl)carbamate

 

InChi Key: 

HTOYBIILVCHURC-UHFFFAOYSA-N

 

InChi Code: InChI=1S/C15H22N2O3/c1-2-20-15(19)17-11-6-9-14(18)16-12-10-13-7-4-3-5-8-13/h3-5,7-8H,2,6,9-12H2,1H3,(H,16,18)(H,17,19)

 

Smiles Code:

O=C(NCCC1=CC=CC=C1)CCCNC(OCC)=O

 

 

Technical Data:

 

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

 

 

References:

 

  1. Pavlik et al (2013) Santacruzamate A, a potent and selective histone deacetylase inhibitor from the Panamanian marine cyanobacterium cf. Symploca sp. J.Nat.Prod. 76 2026 PMID: 24164245

 

  1. Gordon et al (2020) A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Nature. 583 459 PMID: 32353859

 

Products are for research use only. Not for human use.

Payment & Security

American Express Apple Pay Diners Club Discover Elo Google Pay JCB Mastercard PayPal Shop Pay Venmo Visa

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed