GX 201


Catalog No. size PriceQuantity
M7184-2 2mg solid $110
M7184-10 10mg solid $441

Description

Cas:1788071-27-1

Product Information:

GX 201 is a potent and selective Nav1.7 blocker and an analgesic.

 

Chemical Formula: C25H27ClF4N2O4S

 

Exact Mass: 562.1316

 

Molecular Weight: 563.0046

 

Elemental Analysis: C, 53.33; H, 4.83; Cl, 6.30; F, 13.50; N, 4.98; O, 11.37; S, 5.69

 

Synonym: 

 

GX 201

GX-201

GX201

 

Chemical Name: 4-[[1-[[2-Chloro-5-(trifluoromethyl)phenyl]methyl]-4-piperidinyl]methoxy]-5-cyclopropyl-2-fluoro-N-(methylsulfonyl)benzamide

 

InChi Key: 

KYBPOTYVFWNSGS-UHFFFAOYSA-N

 

InChi Code: InChI=1S/C25H27ClF4N2O4S/c1-37(34,35)31-24(33)20-11-19(16-2-3-16)23(12-22(20)27)36-14-15-6-8-32(9-7-15)13-17-10-18(25(28,29)30)4-5-21(17)26/h4-5,10-12,15-16H,2-3,6-9,13-14H2,1H3,(H,31,33)

 

Smiles Code:

O=C(NS(=O)(C)=O)C1=CC(C2CC2)=C(OCC3CCN(CC4=CC(C(F)(F)F)=CC=C4Cl)CC3)C=C1F

 

 

Technical Data:

 

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

 

 

References

 

  1. Shields SD, Deng L, Reese RM, et al. Insensitivity to Pain upon Adult-Onset Deletion of Nav1.7 or Its Blockade with Selective Inhibitors. J Neurosci. 2018;38(47):10180-10201. doi:10.1523/JNEUROSCI.1049-18.2018

 

  1. Bankar G, Goodchild SJ, Howard S, et al. Selective NaV1.7 Antagonists with Long Residence Time Show Improved Efficacy against Inflammatory and Neuropathic Pain. Cell Rep. 2018;24(12):3133-3145. doi:10.1016/j.celrep.2018.08.063

 

Products are for research use only. Not for human use.

Payment & Security

American Express Apple Pay Diners Club Discover Elo Google Pay JCB Mastercard PayPal Shop Pay Venmo Visa

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed