Pomalidomide 4-alkylC8-acid

Cas：2305936-70-1

Product Information：

Pomalidomide 4-alkylC8-acid is a cereblon ligand with alkyl linker and terminal acid for onward chemistry. It is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus an alkylC8 linker with terminal acid ready for conjugation to a target protein ligand. It is part of a range of functionalized tool molecules for PROTAC R&D.

Chemical Formula: C20H23N3O8

Exact Mass: 433.1485

Molecular Weight: 433.417

Elemental Analysis: C, 55.42; H, 5.35; N, 9.70; O, 29.53

Synonym:

Pomalidomide 4-alkylC8-acid

Pomalidomide4-alkylC8acid

Pomalidomide4-alkylC8

Chemical Name: 9-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)nonanoic acid

InChi Key:

OGMJVYCYINHWEJ-UHFFFAOYSA-N

InChi Code: InChI=1S/C22H27N3O6/c26-17-12-11-16(20(29)24-17)25-21(30)14-8-7-9-15(19(14)22(25)31)23-13-6-4-2-1-3-5-10-18(27)28/h7-9,16,23H,1-6,10-13H2,(H,27,28)(H,24,26,29)

Smiles Code:

OC(CCCCCCCCNC1=C2C(N(C3CCC(NC3=O)=O)C(C2=CC=C1)=O)=O)=O

Technical Data：

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Products are for research use only. Not for human use.