Pomalidomide 4-alkylC8-acid

Pomalidomide 4-alkylC8-acid is a cereblon ligand with alkyl linker and terminal acid for onward chemistry. It is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus an alkylC8 linker with terminal acid ready for conjugation to a target protein ligand. It is part of a range of functionalized tool molecules for PROTAC R&D.

Product information

CAS Number: 2305936-70-1

Molecular Weight: 429.47

Formula: C22H27N3O6

Synonym:

Pomalidomide4-alkylC8acid

Pomalidomide4-alkylC8

Pomalidomide 4-alkylC8-acid

Chemical Name: 9-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)nonanoic acid

Smiles: OC(=O)CCCCCCCCNC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O

InChiKey: OGMJVYCYINHWEJ-UHFFFAOYSA-N

InChi: InChI=1S/C22H27N3O6/c26-17-12-11-16(20(29)24-17)25-21(30)14-8-7-9-15(19(14)22(25)31)23-13-6-4-2-1-3-5-10-18(27)28/h7-9,16,23H,1-6,10-13H2,(H,27,28)(H,24,26,29)

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

Products are for research use only. Not for human use.