Pomalidomide 4-PEG1-acid


Catalog No. size PriceQuantity
M7196-2 2mg solid $91
M7196-10 10mg solid $368

Description

Cas:2139348-60-8

Product Information

Pomalidomide 4-PEG1-acid is a cereblon ligand with PEG linker and terminal acid for onward chemistry.

 

Chemical Formula: C18H19N3O7

 

Exact Mass: 389.1223

 

Molecular Weight: 389.364

 

Elemental Analysis: C, 55.53; H, 4.92; N, 10.79; O, 28.76

 

Synonym:

 

Pomalidomide 4-PEG1-acid

Pomalidomide4-PEG1acid

Pomalidomide 4PEG1

Pomalidomide4PEG1acid

 

Chemical Name: 3-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)propanoic acid

 

InChi Key:

GXCGXOBFROXMLV-UHFFFAOYSA-N

 

InChi Code: InChI=1S/C18H19N3O7/c22-13-5-4-12(16(25)20-13)21-17(26)10-2-1-3-11(15(10)18(21)27)19-7-9-28-8-6-14(23)24/h1-3,12,19H,4-9H2,(H,23,24)(H,20,22,25)

 

Smiles Code:

OC(CCOCCNC1=C2C(N(C3CCC(NC3=O)=O)C(C2=CC=C1)=O)=O)=O

 

 

Technical Data:

 

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

 

 

References

 

  1. Qiu X, et al. Jiang B. Chemoselective Synthesis of Lenalidomide-Based PROTAC Library Using Alkylation Reaction. Org Lett. 2019;21(10):3838-3841.

 

Products are for research use only. Not for human use.

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