Catalog No. size PriceQuantity
M7219-2 2mg solid $83
M7219-10 10mg solid $324


Lopinavir is an HIV protease inhibitor used in a fixed-dose combination with Ritonavir. It is used against HIV infections as a fixed-dose combination with another protease inhibitor, ritonavir, under the trade names Kaletra and Aluvia. It was first approved by the FDA on 15 September 2000.

Product information

CAS Number: 192725-17-0

Molecular Weight: 628.80

Formula: C37H48N4O5







ABT 378

A 157378.0



Chemical Name: (2S)-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide

Smiles: CC(C)[C@@H](C(=O)N[C@H](C[C@H](O)[C@H](CC1=CC=CC=C1)NC(=O)COC1=C(C)C=CC=C1C)CC1=CC=CC=C1)N1CCCNC1=O


InChi: InChI=1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t30-,31-,32-,34-/m0/s1

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO, not in water

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200


  1. Aline F, Aurélie R, Matthias C, Olivier B, Thierry B, Paule SM, Chantal C. Comparison of population pharmacokinetics based on steady-state assumption versus electronically monitored adherence to lopinavir, atazanavir, efavirenz, and etravirine: A retrospective study. Ther Drug Monit. 2016 Mar 1. [Epub ahead of print] PubMed PMID: 26937748.
  2. Raposo LM, Arruda MB, de Brindeiro RM, Nobre FF. Lopinavir Resistance Classification with Imbalanced Data Using Probabilistic Neural Networks. J Med Syst. 2016 Mar;40(3):69. doi: 10.1007/s10916-015-0428-7. Epub 2016 Jan 6. PubMed PMID: 26733278.
  3. Patel G, Shelat P, Lalwani A. Statistical modeling, optimization and characterization of solid self-nanoemulsifying drug delivery system of lopinavir using design of experiment. Drug Deliv. 2016 Feb 16:1-16. [Epub ahead of print] PubMed PMID: 26882014.

Products are for research use only. Not for human use.

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