SB297006, an antagonist of C-C chemokine receptor 3 (CCR3)

Catalog No. Size PriceQuantity
M7242-2 2mg solid $80
M7242-10 10mg solid $240


SB297006 is a selective antagonist of CCR3 with IC50 of 39 nM

Product information

CAS Number: 58816-69-6

Molecular Weight: 342.35

Formula: C18H18N2O5

Chemical Name: N-benzoyl-4-nitro-L-phenylalanine, ethyl ester

Smiles: CCOC(=O)[C@H](CC1C=CC(=CC=1)[N+]([O-])=O)NC(=O)C1C=CC=CC=1


InChi: InChI=1S/C18H18N2O5/c1-2-25-18(22)16(19-17(21)14-6-4-3-5-7-14)12-13-8-10-15(11-9-13)20(23)24/h3-11,16H,2,12H2,1H3,(H,19,21)/t16-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 68 mg/mL(198.62 mM). Water: Insoluble.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

SB297006 is a CCR3 antagonist, significantly inhibits proliferation and neurosphere formation in CCL11-treated neural progenitor cells (NPCs) at 100 μM[1].


  1. Wang F, et al. CCL11 promotes migration and proliferation of mouse neural progenitor cells. Stem Cell Res Ther. 2017 Feb 7;8(1):26.

Products are for research use only. Not for human use.

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