CID 1375606

Catalog No. Size PriceQuantity
M7261-2 2mg solid $80
M7261-10 10mg solid $335


CID 1375606 is an agonist of GPR27 SREB1 that induces coupling of the receptor to arrestin 2

Product information

CAS Number: 313493-80-0

Molecular Weight: 385.24

Formula: C20H14Cl2N2O2

Chemical Name: 2,4-Dichloro-N-(phenylcarbamoyl)phenylbenzamide

Smiles: O=C(C1=CC=C(Cl)C=C1Cl)N(C1C=CC=CC=1)C(=O)NC1C=CC=CC=1


InChi: InChI=1S/C20H14Cl2N2O2/c21-14-11-12-17(18(22)13-14)19(25)24(16-9-5-2-6-10-16)20(26)23-15-7-3-1-4-8-15/h1-13H,(H,23,26)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 77 mg/mL(199.87 mM). Water: Insoluble.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

CID 1375606 is a GPR27-specific surrogate agonist. GPR27 is characterized by a high level of conservation among vertebrates and a predominant expression in the central nervous system. In addition, it has recently been linked to insulin secretion[1].


  1. Dupuis N, et al. Activation of the Orphan G Protein-Coupled Receptor GPR27 by Surrogate Ligands Promotes β-Arrestin 2 Recruitment. Mol Pharmacol. 2017 Jun;91(6):595-608.

Products are for research use only. Not for human use.

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