ZD 7155 HCl

Catalog No. Size PriceQuantity
M7275-2 2mg solid $85
M7275-10 10mg solid $255


ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.

Product information

CAS Number: 146709-78-6

Molecular Weight: 474.99

Formula: C26H27ClN6O

Chemical Name: 5,7-diethyl-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1,2,3,4-tetrahydro-1,6-naphthyridin-2-one hydrochloride

Smiles: Cl.CCC1=CC2=C(CCC(=O)N2CC2C=CC(=CC=2)C2=CC=CC=C2C2NN=NN=2)C(CC)=N1


InChi: InChI=1S/C26H26N6O.ClH/c1-3-19-15-24-22(23(4-2)27-19)13-14-25(33)32(24)16-17-9-11-18(12-10-17)20-7-5-6-8-21(20)26-28-30-31-29-26;/h5-12,15H,3-4,13-14,16H2,1-2H3,(H,28,29,30,31);1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 250 mg/mL (526.33 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

ZD 7155 and losartan behave as competitive antagonists and the pressor response curve to angiotensin II is shifted to the right in conscious SD rats. Experiments in conscious SD rats also show that ZD 7155 is approximately ten times as potent as losartan in suppressing the angiotensin II-induced pressor response (240 ng/kg; 10 min infusion).


  1. Junggren IL, et al. Comparative cardiovascular effects of the angiotensin II type 1 receptor antagonists ZD 7155 and losartan in the rat. J Pharm Pharmacol. 1996 Aug;48(8):829-33.

Products are for research use only. Not for human use.

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