PPQ-102


Catalog No. Size PriceQuantity
M7301-2 2mg solid $85
M7301-10 10mg solid $255

Description

PPQ-102 is a potent and voltage-independent CFTR inhibitor which completely inhibit CFTR chloride current with IC50 approximately 90 nM

Product information

CAS Number: 931706-15-9

Molecular Weight: 438.48

Formula: C26H22N4O3

Chemical Name: 7,9-dimethyl-6-(5-methylfuran-2-yl)-11-phenyl-5,6-dihydropyrimido[4',5':3,4]pyrrolo[1,2-a]quinoxaline-8,10(7H,9H)-dione

Smiles: CC1=CC=C(O1)C1NC2=CC=CC=C2N2C(=C3C(=C21)N(C)C(=O)N(C)C3=O)C1C=CC=CC=1

InChiKey: MNOOVRNGPIWJDI-UHFFFAOYSA-N

InChi: InChI=1S/C26H22N4O3/c1-15-13-14-19(33-15)21-24-23-20(25(31)29(3)26(32)28(23)2)22(16-9-5-4-6-10-16)30(24)18-12-8-7-11-17(18)27-21/h4-14,21,27H,1-3H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 50 mg/mL(114.03 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Lukmanee Tradtrantip, et al. J Med Chem. 2009 Oct 22;52(20):6447-55.

Products are for research use only. Not for human use.

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