NOD-IN-1


Catalog No. Size PriceQuantity
M7303-2 2mg solid $85
M7303-10 10mg solid $255

Description

NOD-IN-1 is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors, NOD1 and NOD2, with IC50 of 5.74 M and 6.45 M, respectively.

Product information

CAS Number: 132819-92-2

Molecular Weight: 343.40

Formula: C18H17NO4S

Chemical Name: ethyl 1-tosyl-1H-indole-2-carboxylate

Smiles: CC1C=CC(=CC=1)S(=O)(=O)N1C2=CC=CC=C2C=C1C(=O)OCC

InChiKey: OJMOGUKIYRAILM-UHFFFAOYSA-N

InChi: InChI=1S/C18H17NO4S/c1-3-23-18(20)17-12-14-6-4-5-7-16(14)19(17)24(21,22)15-10-8-13(2)9-11-15/h4-12H,3H2,1-2H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 69 mg/mL(200.93 mM). Water: Insoluble.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Kecek Plesec K, et al. Identification of indole scaffold-based dual inhibitors of NOD1 and NOD2. Bioorg Med Chem. 2016 Nov 1;24(21):5221-5234.

Products are for research use only. Not for human use.

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