RN-1734


Catalog No. Size PriceQuantity
M7341-2 2mg solid $80
M7341-10 10mg solid $240

Description

RN-1734 is selective antagonist of the TRPV4 channel completely antagonizes 4PDD-mediated activation of TRPV4 with comparable low micromolar IC50 values for all three species hTRPV4 IC50 23 M mTRPV4 IC50 59 M rTRPV4 IC50 32 M

Product information

CAS Number: 946387-07-1

Molecular Weight: 353.31

Formula: C14H22Cl2N2O2S

Chemical Name: 2,4-dichloro-N-(propan-2-yl)-N-{2-[(propan-2-yl)amino]ethyl}benzene-1-sulfonamide

Smiles: CC(C)N(CCNC(C)C)S(=O)(=O)C1=CC=C(Cl)C=C1Cl

InChiKey: IHYZMEAZAIFMTN-UHFFFAOYSA-N

InChi: InChI=1S/C14H22Cl2N2O2S/c1-10(2)17-7-8-18(11(3)4)21(19,20)14-6-5-12(15)9-13(14)16/h5-6,9-11,17H,7-8H2,1-4H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 71 mg/mL(200.95 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Liu M, et al. Front Cell Neurosci. 2018 Nov 5;12:392.
  2. Vincent F, et al. Biochem Biophys Res Commun. 2009 Nov 20;389(3):490-4.

Products are for research use only. Not for human use.

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