Dichlorphenamide


Catalog No. Size PriceQuantity
M7344-2 2mg solid $75
M7344-10 10mg solid $225

Description

Dichlorphenamide is a sulfonamide and an orally bioavailable carbonic anhydrase (CA) inhibitor with Kis of 1.20, 38, 50, and 50 nM for the human CA isoforms CAI, CAII, CAIX, and CAXII, respectively.

Product information

CAS Number: 120-97-8

Molecular Weight: 305.16

Formula: C6H6Cl2N2O4S2

Synonym:

Diclofenamide

Chemical Name: 4,5-dichlorobenzene-1,3-disulfonamide

Smiles: NS(=O)(=O)C1=CC(Cl)=C(Cl)C(=C1)S(N)(=O)=O

InChiKey: GJQPMPFPNINLKP-UHFFFAOYSA-N

InChi: InChI=1S/C6H6Cl2N2O4S2/c7-4-1-3(15(9,11)12)2-5(6(4)8)16(10,13)14/h1-2H,(H2,9,11,12)(H2,10,13,14)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (327.70 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Kanski, J.J., Carbonic anhydrase inhibitors and osmotic agents in glaucoma. Carbonic anhydrase inhibitors. Br J Ophthalmol, 1968. 52(8): p. 642-3.
  2. Rucquoy, M. and L. Sorel, Diclofenamide in the treatment of therapy-resistant epilepsy. Acta Neurol Belg, 1978. 78(3): p. 174-82.

Products are for research use only. Not for human use.

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