Ertugliflozin L-pyroglutamic Acid

Catalog No. Size PriceQuantity
M7352-2 2mg solid $85
M7352-10 10mg solid $255


Ertugliflozin L-pyroglutamic acid (PF-04971729 L-pyroglutamic acid) is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2), with an IC50 of 0.877 nM for h-SGLT2[1]. A drug for the treatment of type 2 diabetes mellitus[2].

Product information

CAS Number: 1210344-83-4

Molecular Weight: 566.00

Formula: C27H32ClNO10

Chemical Name: (S)-5-oxopyrrolidine-2-carboxylic acid compound with (1S,2S,3S,4R,5S)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol (1:1)

Smiles: CCOC1C=CC(CC2=CC(=CC=C2Cl)[C@@]23O[C@](CO2)(CO)C(O)[C@H](O)[C@H]3O)=CC=1.OC(=O)[C@@H]1CCC(=O)N1


InChi: InChI=1S/C22H25ClO7.C5H7NO3/c1-2-28-16-6-3-13(4-7-16)9-14-10-15(5-8-17(14)23)22-20(27)18(25)19(26)21(11-24,30-22)12-29-22;7-4-2-1-3(6-4)5(8)9/h3-8,10,18-20,24-27H,2,9,11-12H2,1H3;3H,1-2H2,(H,6,7)(H,8,9)/t18-,19?,20+,21-,22-;3-/m00/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 100 mg/mL(176.67 mM). Water: 10 mg/mL(17.66 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Meiyan Jiang, Peter S Steyger. Expert Opin Ther Pat. 2015;25(11):1349-52.

Products are for research use only. Not for human use.

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