4,4,4-Trifluoro-1-(thiophen-2-yl)-2-(2-(m-tolyl)hydrazono)butane-1,3-dione


Catalog No. Size PriceQuantity
M7367-2 2mg solid $80
M7367-10 10mg solid $240

Description

GR148672X is a triacyglycerol hydrolase (TGH) inhibitor with an IC50 of 4 nM extracted from patent WO 2001016358 A2.

Product information

CAS Number: 263890-70-6

Molecular Weight: 340.32

Formula: C15H11F3N2O2S

Chemical Name: (2Z)-4,4,4-trifluoro-2-[2-(3-methylphenyl)hydrazin-1-ylidene]-1-(thiophen-2-yl)butane-1,3-dione

Smiles: CC1=CC(=CC=C1)N/N=C(\C(=O)C1=CC=CS1)/C(=O)C(F)(F)F

InChiKey: YNUQHMHMYSUKFL-UDWIEESQSA-N

InChi: InChI=1S/C15H11F3N2O2S/c1-9-4-2-5-10(8-9)19-20-12(14(22)15(16,17)18)13(21)11-6-3-7-23-11/h2-8,19H,1H3/b20-12+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 41.67 mg/mL (122.44 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Catherine Sylvia Borg-Capra, et al. Method of screening for triacyglycerol hydrolase inhibitors . WO 2001016358 A2.

Products are for research use only. Not for human use.

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