UCB9608


Catalog No. Size PriceQuantity
M7372-2 2mg solid $100
M7372-10 10mg solid $340

Description

UCB9608 (compound 44) is a potent, selective and orally bioavailable inhibitor of PI4KIIIβ with IC50 of 11 nM. UCB9608 is a potent immunosuppressive agent that improves metabolic stability and exhibits excellent pharmacokinetic profile.

Product information

CAS Number: 1616413-96-7

Molecular Weight: 410.47

Formula: C20H26N8O2

Chemical Name: (3S)-4-(6-amino-1-methyl-pyrazolo[3, 4-d]pyrimidin-4-yl)-N-(4-methoxy-2-methyl-phenyl)-3-methyl-piperazine-1-carboxamide

Smiles: CN1N=CC2=C1N=C(N)N=C2N1CCN(C[C@@H]1C)C(=O)NC1=CC=C(C=C1C)OC

InChiKey: WRONAJQPZWDYAR-ZDUSSCGKSA-N

InChi: InChI=1S/C20H26N8O2/c1-12-9-14(30-4)5-6-16(12)23-20(29)27-7-8-28(13(2)11-27)18-15-10-22-26(3)17(15)24-19(21)25-18/h5-6,9-10,13H,7-8,11H2,1-4H3,(H,23,29)(H2,21,24,25)/t13-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 82 mg/mL(199.77 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. James Reuberson, et al. J Med Chem. 2018 Aug 9;61(15):6705-6723.

Products are for research use only. Not for human use.

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