Description
BD750 is an immunosuppressant and a dual inhibitor of JAK3 and STAT5 that inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation with IC50 of 1.5 μM and 1.1 μM for mouse and human T-cell proliferation, respectively.
Product information
CAS Number: 892686-59-8
Molecular Weight: 271.34
Formula: C14H13N3OS
Chemical Name: 2-(1, 3-benzothiazol-2-yl)-4, 5, 6, 7-tetrahydro-1H-indazol-3-one
Smiles: O=C1C2CCCCC=2NN1C1=NC2=CC=CC=C2S1
InChiKey: QWUHPPCZZXKXOQ-UHFFFAOYSA-N
InChi: InChI=1S/C14H13N3OS/c18-13-9-5-1-2-6-10(9)16-17(13)14-15-11-7-3-4-8-12(11)19-14/h3-4,7-8,16H,1-2,5-6H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO: 30 mg/mL(110.56 mM).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Y Liu, et al. Br J Pharmacol. 2013 Feb;168(3):632-43.
Products are for research use only. Not for human use.
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