BD750


Catalog No. Size PriceQuantity
M7382-2 2mg solid $80
M7382-10 10mg solid $240
M7382-100 100mg solid $1,440

Description

BD750 is an immunosuppressant and a dual inhibitor of JAK3 and STAT5 that inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation with IC50 of 1.5 μM and 1.1 μM for mouse and human T-cell proliferation, respectively.

Product information

CAS Number: 892686-59-8

Molecular Weight: 271.34

Formula: C14H13N3OS

Chemical Name: 2-(1, 3-benzothiazol-2-yl)-4, 5, 6, 7-tetrahydro-1H-indazol-3-one

Smiles: O=C1C2CCCCC=2NN1C1=NC2=CC=CC=C2S1

InChiKey: QWUHPPCZZXKXOQ-UHFFFAOYSA-N

InChi: InChI=1S/C14H13N3OS/c18-13-9-5-1-2-6-10(9)16-17(13)14-15-11-7-3-4-8-12(11)19-14/h3-4,7-8,16H,1-2,5-6H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 30 mg/mL(110.56 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Y Liu, et al. Br J Pharmacol. 2013 Feb;168(3):632-43.

Products are for research use only. Not for human use.

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