Catalog No. Size PriceQuantity
M7383-2 2mg solid $85
M7383-10 10mg solid $255
M7383-100 100mg solid $1,530


GDC046 (Compound 3) is a potent, selective, and orally bioavailable inhibitor of TYK2 with Ki of 4.8 nM, 83.8 nM, 27.6 nM and 253 nM for TYK2, JAK1, JAK2, and JAK3, respectively.

Product information

CAS Number: 1258292-64-6

Molecular Weight: 350.20

Formula: C16H13Cl2N3O2

Chemical Name: 2, 6-dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide

Smiles: O=C(NC1=CC(NC(=O)C2CC2)=NC=C1)C1C(Cl)=CC=CC=1Cl


InChi: InChI=1S/C16H13Cl2N3O2/c17-11-2-1-3-12(18)14(11)16(23)20-10-6-7-19-13(8-10)21-15(22)9-4-5-9/h1-3,6-9H,4-5H2,(H2,19,20,21,22,23)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 70 mg/mL(199.88 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Jun Liang, et al. J Med Chem. 2013 Jun 13;56(11):4521-36.

Products are for research use only. Not for human use.

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