Ginkgolic acid C17:1


Catalog No. Size PriceQuantity
M7385-2 2mg solid $115
M7385-10 10mg solid $390
M7385-100 100mg solid $2,650

Description

Ginkgolic acid C17:1 (GAC 17:1) inhibits constitutive activation of STAT3 through the abrogation of upstream JAK2 and Src. Ginkgolic acid C17:1 can induce the substantial expression of PTEN and SHP-1. Ginkgolic acid C17:1 induces apoptosis of tumor cells.

Product information

CAS Number: 111047-30-4

Molecular Weight: 374.56

Formula: C24H38O3

Chemical Name: 2-[(Z)-heptadec-10-enyl]-6-hydroxybenzoic acid

Smiles: CCCCCCC=CCCCCCCCCCC1=CC=CC(O)=C1C(O)=O

InChiKey: MBYNDKVOZOAOIS-BQYQJAHWSA-N

InChi: InChI=1S/C24H38O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18-21-19-17-20-22(25)23(21)24(26)27/h7-8,17,19-20,25H,2-6,9-16,18H2,1H3,(H,26,27)/b8-7+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 75 mg/mL(200.23 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Baek SH, et al. Ginkgolic Acid C 17:1, Derived from Ginkgo biloba Leaves, Suppresses Constitutive and Inducible STAT3 Activation through Induction of PTEN and SHP-1 Tyrosine Phosphatase. Molecules. 2017 Feb 13;22(2). pii: E276.

Products are for research use only. Not for human use.

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