Catalog No. Size PriceQuantity
M7389-2 2mg solid $100
M7389-10 10mg solid $300
M7389-100 100mg solid $1,800


SAR-20347 is a potent inhibitor of TYK2, JAK1, JAK2 and JAK3 with IC50 of 0.6 nM, 23 nM, 26 nM and 41 nM, respectively. SAR-20347 inhibits TYK2- and JAK1-mediated IL-12 and IFN-α signaling.

Product information

CAS Number: 1450881-55-6

Molecular Weight: 444.84

Formula: C21H18ClFN4O4

Chemical Name: 2-(2-Chloro-6-fluorophenyl)-5-[[4-(4-morpholinylcarbonyl)phenyl]amino]-4-oxazolecarboxamide

Smiles: NC(=O)C1N=C(OC=1NC1=CC=C(C=C1)C(=O)N1CCOCC1)C1=C(F)C=CC=C1Cl


InChi: InChI=1S/C21H18ClFN4O4/c22-14-2-1-3-15(23)16(14)19-26-17(18(24)28)20(31-19)25-13-6-4-12(5-7-13)21(29)27-8-10-30-11-9-27/h1-7,25H,8-11H2,(H2,24,28)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 89 mg/mL(200.07 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Melissa G Works, et al. J Immunol. 2014 Oct 1;193(7):3278-87.

Products are for research use only. Not for human use.

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