Catalog No. Size PriceQuantity
M7395-2 2mg solid $240
M7395-10 10mg solid $960
M7395-100 100mg solid $7,680


Oncrasin-1 (Onc-1) is a potent RNA polymerase II inhibitor with antitumor activity that kills various human lung cancer cells with K-Ras mutations. Oncrasin-1 drives abnormal aggregation of protein kinase C iota (PKCι) in nucleus of sensitive cells but not in resistant cells.

Product information

CAS Number: 75629-57-1

Molecular Weight: 269.73

Formula: C16H12ClNO

Chemical Name: 1-(4-Chlorobenzyl)-1H-indole-3-carbaldehyde

Smiles: O=CC1=CN(CC2C=CC(Cl)=CC=2)C2=CC=CC=C21


InChi: InChI=1S/C16H12ClNO/c17-14-7-5-12(6-8-14)9-18-10-13(11-19)15-3-1-2-4-16(15)18/h1-8,10-11H,9H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Wei Guo, et al. Cancer Res. 2008 Sep 15;68(18):7403-8.
  2. Shuhong Wu, et al. J Med Chem. 2011 Apr 28;54(8):2668-79.

Products are for research use only. Not for human use.

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