Oncrasin-1


Catalog No. Size PriceQuantity
M7395-2 2mg solid $240
M7395-10 10mg solid $960
M7395-100 100mg solid $7,680

Description

Oncrasin-1 (Onc-1) is a potent RNA polymerase II inhibitor with antitumor activity that kills various human lung cancer cells with K-Ras mutations. Oncrasin-1 drives abnormal aggregation of protein kinase C iota (PKCι) in nucleus of sensitive cells but not in resistant cells.

Product information

CAS Number: 75629-57-1

Molecular Weight: 269.73

Formula: C16H12ClNO

Chemical Name: 1-(4-Chlorobenzyl)-1H-indole-3-carbaldehyde

Smiles: O=CC1=CN(CC2C=CC(Cl)=CC=2)C2=CC=CC=C21

InChiKey: ZDRQMXCSSAPUMM-UHFFFAOYSA-N

InChi: InChI=1S/C16H12ClNO/c17-14-7-5-12(6-8-14)9-18-10-13(11-19)15-3-1-2-4-16(15)18/h1-8,10-11H,9H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Wei Guo, et al. Cancer Res. 2008 Sep 15;68(18):7403-8.
  2. Shuhong Wu, et al. J Med Chem. 2011 Apr 28;54(8):2668-79.

Products are for research use only. Not for human use.

Payment & Security

American Express Diners Club Discover JCB Mastercard PayPal Venmo Visa

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed