Catalog No. Size PriceQuantity
M7408-2 2mg solid $90
M7408-10 10mg solid $270
M7408-100 100mg solid $1,620


RG3039 (PF-06687859, PF 6687859, Quinazoline 495) is an orally bioavailable and brain-penetrant inhibitor of the mRNA decapping enzyme DcpS with IC50 of 4.2 nM and IC90 of 40 nM, respectively.

Product information

CAS Number: 1005504-62-0

Molecular Weight: 432.35

Formula: C21H23Cl2N5O



Chemical Name: 5-((1-(2,6-dichlorobenzyl)piperidin-4-yl)methoxy)quinazoline-2,4-diamine

Smiles: NC1=NC(N)=NC2=CC=CC(OCC3CCN(CC4C(Cl)=CC=CC=4Cl)CC3)=C12


InChi: InChI=1S/C21H23Cl2N5O/c22-15-3-1-4-16(23)14(15)11-28-9-7-13(8-10-28)12-29-18-6-2-5-17-19(18)20(24)27-21(25)26-17/h1-6,13H,7-12H2,(H4,24,25,26,27)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 3 mg/mL(6.93 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Rocky G Gogliotti, et al. Hum Mol Genet. 2013 Oct 15;22(20):4084-101.

Products are for research use only. Not for human use.

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