Catalog No. Size PriceQuantity
M7454-2 2mg solid $110
M7454-10 10mg solid $330


CBL0137 (Curaxin-137) is an inhibitor of the histone chaperone FACT (facilitates chromatin transcription) that simultaneously suppresses NF-κB and activates p53 with EC50 of 0.47 μM and 0.37 μM, respectively.

Product information

CAS Number: 1197996-80-7

Molecular Weight: 336.43

Formula: C21H24N2O2





Chemical Name: 1,1'-(9-(2-(isopropylamino)ethyl)-9H-carbazole-3,6-diyl)bis(ethan-1-one)

Smiles: CC(C)NCCN1C2=CC=C(C=C2C2=CC(=CC=C12)C(C)=O)C(C)=O


InChi: InChI=1S/C21H24N2O2/c1-13(2)22-9-10-23-20-7-5-16(14(3)24)11-18(20)19-12-17(15(4)25)6-8-21(19)23/h5-8,11-13,22H,9-10H2,1-4H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO 15 mg/mL (44.59 mM) Ethanol 8 mg/mL (23.78 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Alexander V Gasparian, et al. Sci Transl Med. 2011 Aug 10;3(9

Products are for research use only. Not for human use.

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