RP-64477


Catalog No. Size PriceQuantity
M7464-2 2mg solid $460
M7464-10 10mg solid $1,840

Description

RP-64477 is a potent inhibitor of the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT). RP-64477 inhibits ACAT activity with IC50 of 113 nM, 503 nM, and 180 nM in human intestinal (CaCo-2), hepatic (HepG2) and monocytic (THP-1) cell assays, respectively.

Product information

CAS Number: 135239-65-5

Molecular Weight: 498.72

Formula: C29H42N2O3S

Chemical Name: N'-Butyl-4-(decyloxy)-4'-(methylthio)-N,3'-bibenzamide

Smiles: CCCCCCCCCCOC1C=CC(=CC=1)C(=O)NC1=CC(=CC=C1SC)C(=O)NCCCC

InChiKey: OZMWNRSILHTVFV-UHFFFAOYSA-N

InChi: InChI=1S/C29H42N2O3S/c1-4-6-8-9-10-11-12-13-21-34-25-17-14-23(15-18-25)29(33)31-26-22-24(16-19-27(26)35-3)28(32)30-20-7-5-2/h14-19,22H,4-13,20-21H2,1-3H3,(H,30,32)(H,31,33)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO 100 mg/mL (200.51 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. A A Bello, et al. Biochem Pharmacol. 1996 Feb 23;51(4):413-21.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed