Sacubitrilat


Catalog No. Size PriceQuantity
M7472-2 2mg solid $105
M7472-10 10mg solid $390

Description

Sacubitrilat (Sac, LBQ-657) is an active inhibitor of neprilysin (NEP).

Product information

CAS Number: 149709-44-4

Molecular Weight: 383.44

Formula: C22H25NO5

Synonym:

Sac

LBQ-657

Chemical Name: (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(3-carboxypropanamido)-2-methylpentanoic acid

Smiles: C[C@H](C[C@@H](CC1=CC=C(C=C1)C1=CC=CC=C1)NC(=O)CCC(O)=O)C(O)=O

InChiKey: DOBNVUFHFMVMDB-BEFAXECRSA-N

InChi: InChI=1S/C22H25NO5/c1-15(22(27)28)13-19(23-20(24)11-12-21(25)26)14-16-7-9-18(10-8-16)17-5-3-2-4-6-17/h2-10,15,19H,11-14H2,1H3,(H,23,24)(H,25,26)(H,27,28)/t15-,19+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO 77 mg/mL (200.81 mM) Ethanol 77 mg/mL (200.81 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Surya P Ayalasomayajula, et al. Eur J Clin Pharmacol. 2016 Sep

Products are for research use only. Not for human use.

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