Description
T-26c is a highly potent and selective inhibitor of matrix metalloproteinase-13 (MMP-13) with IC50 of 6.9 pM, more than 2600-fold selectivity over other related metalloenzymes.
Product information
CAS Number: 869296-13-9
Molecular Weight: 479.51
Formula: C24H21N3O6S
Chemical Name: 4-(((2-((3-methoxybenzyl)carbamoyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-5-yl)methoxy)methyl)benzoic acid
Smiles: COC1=CC(CNC(=O)C2NC(=O)C3=C(N=2)SC=C3COCC2C=CC(=CC=2)C(O)=O)=CC=C1
InChiKey: CDQRIIUMNLMHRH-UHFFFAOYSA-N
InChi: InChI=1S/C24H21N3O6S/c1-32-18-4-2-3-15(9-18)10-25-22(29)20-26-21(28)19-17(13-34-23(19)27-20)12-33-11-14-5-7-16(8-6-14)24(30)31/h2-9,13H,10-12H2,1H3,(H,25,29)(H,30,31)(H,26,27,28)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO 40 mg/mL (83.42 mM)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Hiroshi Nara, et al. Bioorg Med Chem. 2014 Oct 1;22(19):5487-5
Products are for research use only. Not for human use.
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