T-26c


Catalog No. Size PriceQuantity
M7475-2 2mg solid $105
M7475-10 10mg solid $360

Description

T-26c is a highly potent and selective inhibitor of matrix metalloproteinase-13 (MMP-13) with IC50 of 6.9 pM, more than 2600-fold selectivity over other related metalloenzymes.

Product information

CAS Number: 869296-13-9

Molecular Weight: 479.51

Formula: C24H21N3O6S

Chemical Name: 4-(((2-((3-methoxybenzyl)carbamoyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-5-yl)methoxy)methyl)benzoic acid

Smiles: COC1=CC(CNC(=O)C2NC(=O)C3=C(N=2)SC=C3COCC2C=CC(=CC=2)C(O)=O)=CC=C1

InChiKey: CDQRIIUMNLMHRH-UHFFFAOYSA-N

InChi: InChI=1S/C24H21N3O6S/c1-32-18-4-2-3-15(9-18)10-25-22(29)20-26-21(28)19-17(13-34-23(19)27-20)12-33-11-14-5-7-16(8-6-14)24(30)31/h2-9,13H,10-12H2,1H3,(H,25,29)(H,30,31)(H,26,27,28)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO 40 mg/mL (83.42 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Hiroshi Nara, et al. Bioorg Med Chem. 2014 Oct 1;22(19):5487-5

Products are for research use only. Not for human use.

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