Description
SEL-201 (SLV-2436, SEL201-88) is a highly potent and ATP-competitive inhibitor of MNK1 and MNK2 with IC50 of 10.8 nM and 5.4 nM, respectively.
Product information
CAS Number: 2095704-43-9
Molecular Weight: 350.80
Formula: C19H15ClN4O
Synonym:
SLV-2436
SLV 2436
SLV2436
SEL201-88
Chemical Name: 5-(3-amino-1H-indazol-6-yl)-1-(3-chlorobenzyl)pyridin-2(1H)-one
Smiles: NC1=NNC2=CC(=CC=C21)C1=CN(CC2=CC(Cl)=CC=C2)C(=O)C=C1
InChiKey: YQVUADHJKWJHAF-UHFFFAOYSA-N
InChi: InChI=1S/C19H15ClN4O/c20-15-3-1-2-12(8-15)10-24-11-14(5-7-18(24)25)13-4-6-16-17(9-13)22-23-19(16)21/h1-9,11H,10H2,(H3,21,22,23)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO 70 mg/mL (199.54 mM) Ethanol 5 mg/mL (14.25 mM)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Yao Zhan, et al. J Clin Invest. 2017 Nov 1;127(11):4179-4192.
Products are for research use only. Not for human use.
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