SEL201


Catalog No. Size PriceQuantity
M7503-2 2mg solid $165
M7503-10 10mg solid $660

Description

SEL-201 (SLV-2436, SEL201-88) is a highly potent and ATP-competitive inhibitor of MNK1 and MNK2 with IC50 of 10.8  nM and 5.4 nM, respectively.

Product information

CAS Number: 2095704-43-9

Molecular Weight: 350.80

Formula: C19H15ClN4O

Synonym:

SLV-2436

SLV 2436

SLV2436

SEL201-88

Chemical Name: 5-(3-amino-1H-indazol-6-yl)-1-(3-chlorobenzyl)pyridin-2(1H)-one

Smiles: NC1=NNC2=CC(=CC=C21)C1=CN(CC2=CC(Cl)=CC=C2)C(=O)C=C1

InChiKey: YQVUADHJKWJHAF-UHFFFAOYSA-N

InChi: InChI=1S/C19H15ClN4O/c20-15-3-1-2-12(8-15)10-24-11-14(5-7-18(24)25)13-4-6-16-17(9-13)22-23-19(16)21/h1-9,11H,10H2,(H3,21,22,23)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO 70 mg/mL (199.54 mM) Ethanol 5 mg/mL (14.25 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Yao Zhan, et al. J Clin Invest. 2017 Nov 1;127(11):4179-4192.

Products are for research use only. Not for human use.

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