PD 169316


Catalog No. Size PriceQuantity
M7508-2 2mg solid $85
M7508-10 10mg solid $255

Description

PD 169316 is a potent, selective and cell-permeable p38 MAP kinase inhibitor with IC50 of 89 nM. PD169316 abrogates signaling initiated by both TGFbeta and Activin A. PD169316 shows antiviral activity against Enterovirus71.

Product information

CAS Number: 152121-53-4

Molecular Weight: 360.34

Formula: C20H13FN4O2

Chemical Name: 4-(5-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-4-yl)pyridine

Smiles: [O-][N+](=O)C1C=CC(=CC=1)C1NC(=C(N=1)C1C=CN=CC=1)C1C=CC(F)=CC=1

InChiKey: BGIYKDUASORTBB-UHFFFAOYSA-N

InChi: InChI=1S/C20H13FN4O2/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(8-4-15)25(26)27/h1-12H,(H,23,24)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO 14 mg/mL (38.85 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Fu Y, et al. Biochem Biophys Res Commun. 2003 Oct 17;310(2):391-7.
  2. Zhang Z, et al. Virology. 2017 Aug;508:150-158.

Products are for research use only. Not for human use.

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