CZC-8004

CZC-8004 (CZC-00008004) is a pan-kinase inhibitor that binds a range of tyrosine kinases including ABL kinase.

Product information

CAS Number: 916603-07-1

Molecular Weight: 309.34

Formula: C17H16FN5

Synonym:

CZC-00008004

Chemical Name: N2-(4-(aminomethyl)phenyl)-5-fluoro-N4-phenylpyrimidine-2,4-diamine

Smiles: NCC1C=CC(=CC=1)NC1=NC(NC2C=CC=CC=2)=C(F)C=N1

InChiKey: UKOHFWNBTUJMMN-UHFFFAOYSA-N

InChi: InChI=1S/C17H16FN5/c18-15-11-20-17(22-14-8-6-12(10-19)7-9-14)23-16(15)21-13-4-2-1-3-5-13/h1-9,11H,10,19H2,(H2,20,21,22,23)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO 62 mg/mL (200.43 mM) Ethanol 6 mg/mL (19.40 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Fiona M Deane, et al. ACS Omega. 2017 Jul 31;2(7):3828-3838.
2. Marcus Bantscheff, et al. Nat Biotechnol. 2007 Sep;25(9):1035

Products are for research use only. Not for human use.