M1001


Catalog No. Size PriceQuantity
M7512-2 2mg solid $85
M7512-10 10mg solid $255

Description

M1001 is a weak agonist of hypoxia-inducible factor-2α (HIF-2α) that binds to the HIF-2α PAS-B domain with Kd of 667 nM.

Product information

CAS Number: 874590-32-6

Molecular Weight: 327.40

Formula: C17H17N3O2S

Chemical Name: 3-((2-(Pyrrolidin-1-yl)phenyl)amino)benzo[d]isothiazole 1,1-dioxide

Smiles: O=S1(=O)N=C(NC2=CC=CC=C2N2CCCC2)C2=CC=CC=C12

InChiKey: LONXCUOJVJLTIP-UHFFFAOYSA-N

InChi: InChI=1S/C17H17N3O2S/c21-23(22)16-10-4-1-7-13(16)17(19-23)18-14-8-2-3-9-15(14)20-11-5-6-12-20/h1-4,7-10H,5-6,11-12H2,(H,18,19)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO 65 mg/mL (198.53 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Dalei Wu, et al. Nat Chem Biol. 2019 Apr;15(4):367-376.

Products are for research use only. Not for human use.

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