Catalog No. Size PriceQuantity
M7534-2 2mg solid $165
M7534-10 10mg solid $660


GNE-6776 is a potent, non-covalent, selective and orally bioavailable inhibitor of USP7 with IC50 of 1.34 μM and 0.61 μM for full length USP7 and USP7 catalytic domain, respectively.

Product information

CAS Number: 2009273-71-4

Molecular Weight: 348.40

Formula: C20H20N4O2

Chemical Name: 5-[6-amino-4-ethyl-5-(4-hydroxyphenyl)pyridin-3-yl]-N-methylpyridine-2-carboxamide

Smiles: CCC1=C(C(N)=NC=C1C1=CN=C(C=C1)C(=O)NC)C1C=CC(O)=CC=1


InChi: InChI=1S/C20H20N4O2/c1-3-15-16(13-6-9-17(23-10-13)20(26)22-2)11-24-19(21)18(15)12-4-7-14(25)8-5-12/h4-11,25H,3H2,1-2H3,(H2,21,24)(H,22,26)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO 70 mg/mL (200.92 mM) Ethanol 2 mg/mL (5.74 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Lorna Kategaya, et al. Nature. 2017 Oct 26;550(7677):534-538.

Products are for research use only. Not for human use.

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