Catalog No. Size PriceQuantity
M7538-2 2mg solid $210
M7538-10 10mg solid $840


GSK2643943A is an inhibitor of deubiquitylating enzyme (DUB) with IC50 of 160 nM for USP20/Ub-Rho.

Product information

CAS Number: 2449301-27-1

Molecular Weight: 277.30

Formula: C17H12FN3



GSK 2643943A

Chemical Name: (E)-2-amino-6-(3-fluorostyryl)-1H-indole-3-carbonitrile

Smiles: NC1NC2=CC(/C=C/C3=CC(F)=CC=C3)=CC=C2C=1C#N


InChi: InChI=1S/C17H12FN3/c18-13-3-1-2-11(8-13)4-5-12-6-7-14-15(10-19)17(20)21-16(14)9-12/h1-9,21H,20H2/b5-4+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO 55 mg/mL (198.34 mM) Ethanol 8 mg/mL (28.85 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Mark Kemp. Prog Med Chem. 2016;55:149-92.

Products are for research use only. Not for human use.

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