RHC 80267


Catalog No. Size PriceQuantity
M7540-2 2mg solid $90
M7540-10 10mg solid $270

Description

RHC 80267 (U-57908) is a potent and selective inhibitor of diacylglycerol lipase (DAGL, DAG lipase) with IC50 of 4 μM for cholinesterase activity. RHC 80267 inhibits cyclooxygenase (COX) activity, phospholipase C (PLC) activity and the hydrolysis of phosphatidylcholine (PC).

Product information

CAS Number: 83654-05-1

Molecular Weight: 394.51

Formula: C20H34N4O4

Synonym:

RHC80267

RHC-80267

U 57908

U57908

Chemical Name: cyclohexylideneamino N-[6-({[(cyclohexylideneamino)oxy]carbonyl}amino)hexyl]carbamate

Smiles: O=C(NCCCCCCNC(=O)ON=C1CCCCC1)ON=C1CCCCC1

InChiKey: RXSVYGIGWRDVQC-UHFFFAOYSA-N

InChi: InChI=1S/C20H34N4O4/c25-19(27-23-17-11-5-3-6-12-17)21-15-9-1-2-10-16-22-20(26)28-24-18-13-7-4-8-14-18/h1-16H2,(H,21,25)(H,22,26)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO 79 mg/mL (200.25 mM) Ethanol 79 mg/mL (200.25 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Philippe Ghisdal, et al. Eur J Pharmacol. 2005 Jul 4;517(1-2):97-102.
  2. T D Oglesby, R R Gorman. Biochim Biophys Acta. 1984 Apr 18

Products are for research use only. Not for human use.

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