BNC210


Catalog No. Size PriceQuantity
M7545-2 2mg solid $80
M7545-10 10mg solid $240

Description

BNC210 (H-Ile-Trp-OH, IW-2143) is a negative allosteric modulator of alpha-7 nicotinic acetylcholine receptor (α7 nAChR).

Product information

CAS Number: 13589-06-5

Molecular Weight: 317.38

Formula: C17H23N3O3

Synonym:

BNC-210

BNC 210

IW-2143

IW 2143

IW2143

H-ILE-TRP-OH

Isoleucyl-Tryptophan

Chemical Name: (2S)-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid

Smiles: C[C@@H](CC)[C@H](N)C(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O

InChiKey: BVRPESWOSNFUCJ-LKTVYLICSA-N

InChi: InChI=1S/C17H23N3O3/c1-3-10(2)15(18)16(21)20-14(17(22)23)8-11-9-19-13-7-5-4-6-12(11)13/h4-7,9-10,14-15,19H,3,8,18H2,1-2H3,(H,20,21)(H,22,23)/t10-,14-,15-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO 63 mg/mL (198.50 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Toby Wise, et al. Biol Psychiatry. 2020 May 15;87(10):908-915.

Products are for research use only. Not for human use.

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