Catalog No. Size PriceQuantity
M7562-2 2mg solid $140
M7562-10 10mg solid $420


CDK8/19i is a potent and selective CDK8 and CDK19 inhibitor (IC50 values are 2.9 and 14.1 nM, respectively). CDK8/19i maintains pluripotency of mouse PSCs in culture. It induces the formation of dome-shaped colonies and upregulates Nanog-GFP reporter and endogenous Nanog expression in mouse ESCs in vitro.

Product information

CAS Number: 923596-52-5

Molecular Weight: 253.30

Formula: C14H15N5

Chemical Name: N-propyl-3-(pyridin-4-yl)imidazo[1,2-b]pyridazin-6-amine

Smiles: CCCNC1C=CC2=NC=C(C3C=CN=CC=3)N2N=1


InChi: InChI=1S/C14H15N5/c1-2-7-16-13-3-4-14-17-10-12(19(14)18-13)11-5-8-15-9-6-11/h3-6,8-10H,2,7H2,1H3,(H,16,18)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Kazuo Nakai, et al. Fused heterocycles as lck inhibitors. WO2007013673A1.

Products are for research use only. Not for human use.

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