Description
SET2 is a novel selective TRPV2 antagonist. TRPV2 (transient receptor potential vanilloid type 2) antagonist (IC50 = 0.46 μM). Selective for TRPV2 over TRPV1, TRPV3 and TRPV4 expressed in HEK293 cells. Inhibits lyosphosphatidic acid (LPA)-induced prostate cancer cell migration in vitro.
Product information
CAS Number: 2313525-20-9
Molecular Weight: 402.43
Formula: C17H21F3N4O2S
Synonym:
SET2
SET-2
Chemical Name: N-(furan-2-ylmethyl)-3-((4-(methyl(propyl)amino)-6-(trifluoromethyl)pyrimidin-2-yl)thio)propanamide
Smiles: CCCN(C)C1=CC(=NC(=N1)SCCC(=O)NCC1=CC=CO1)C(F)(F)F
InChiKey: LZHSWRWIMQRTOP-UHFFFAOYSA-N
InChi: InChI=1S/C17H21F3N4O2S/c1-3-7-24(2)14-10-13(17(18,19)20)22-16(23-14)27-9-6-15(25)21-11-12-5-4-8-26-12/h4-5,8,10H,3,6-7,9,11H2,1-2H3,(H,21,25)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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