Catalog No. Size PriceQuantity
M7597-2 2mg solid $280
M7597-10 10mg solid $1,110


KAN0438757 is a potent and selective inhibitor of the metabolic kinase PFKFB3 (6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 3) with IC50 of 0.19 μM and 3.6 μM for PFKFB3 and PFKFB4, respectively.

Product information

CAS Number: 1451255-59-6

Molecular Weight: 447.43

Formula: C21H18FNO7S



KAN 0438757

Chemical Name: 2-hydroxyethyl 4-((5'-fluoro-2'-hydroxy-[1,1'-biphenyl])-3-sulfonamido)-2-hydroxybenzoate

Smiles: OCCOC(=O)C1=CC=C(C=C1O)NS(=O)(=O)C1=CC(=CC=C1)C1=CC(F)=CC=C1O


InChi: InChI=1S/C21H18FNO7S/c22-14-4-7-19(25)18(11-14)13-2-1-3-16(10-13)31(28,29)23-15-5-6-17(20(26)12-15)21(27)30-9-8-24/h1-7,10-12,23-26H,8-9H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 7 mg/mL(15.64 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Nina M S Gustafsson, et al. Nat Commun. 2018 Sep 24;9(1):3872.

Products are for research use only. Not for human use.

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