4-Phenylbutyric acid (4-PBA)


Catalog No. Size PriceQuantity
M7598-2 2mg solid $75
M7598-10 10mg solid $225

Description

4-Phenylbutyric acid (4-PBA, Benzenebutyric acid) is a histone deacetylase (HDAC) inhibitor and a key epigenetic inducer of anti-HCV hepatic hepcidin. 4-Phenylbutyric acid inhibits LPS-induced inflammation through regulating endoplasmic-reticulum (ER) stress and autophagy in acute lung injury models.

Product information

CAS Number: 1821-12-1

Molecular Weight: 164.20

Formula: C10H12O2

Synonym:

AI3-12065

AI3 12065

AI312065

Chemical Name: 4-Phenylbutyric acid

Smiles: OC(=O)CCCC1C=CC=CC=1

InChiKey: OBKXEAXTFZPCHS-UHFFFAOYSA-N

InChi: InChI=1S/C10H12O2/c11-10(12)8-4-7-9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2,(H,11,12)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 33 mg/mL(200.97 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Meichun Zeng, et al. Toxicol Lett. 2017 Apr 5;271:26-37.
  2. Kiyoon Kim, et al. Int J Mol Sci. 2020 Aug 1;21(15):5516.

Products are for research use only. Not for human use.

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