Isomalt

Isomalt (Palatinitol) is a sugar alcohol used as an excipient in commercially available solid oral dosage forms. Isomalt stabilizes lactate dehydrogenase (LDH) moderately during freeze-drying.

Product information

CAS Number: 64519-82-0

Molecular Weight: 685.81

Formula: C33H51N9O7

Synonym:

Palatini

Chemical Name: 6-O-alpha-D-Glucopyranosyl-D-glucitol mixed with 1-O-alpha-D-glucopyranosyl-D-mannitol

Smiles: CC(CC)C(NC(=O)C1CCCN1C(=O)C(CC1C=CC=CC=1)NC(=O)C1CCCN1C(=O)CNC(=O)[C@@H](N)CCCNC(N)=N)C(O)=O

InChiKey: NNFNVJXYWKWZTB-RDFDVFKPSA-N

InChi: InChI=1S/C33H51N9O7/c1-3-20(2)27(32(48)49)40-30(46)25-14-9-17-42(25)31(47)23(18-21-10-5-4-6-11-21)39-29(45)24-13-8-16-41(24)26(43)19-38-28(44)22(34)12-7-15-37-33(35)36/h4-6,10-11,20,22-25,27H,3,7-9,12-19,34H2,1-2H3,(H,38,44)(H,39,45)(H,40,46)(H,48,49)(H4,35,36,37)/t20?,22-,23?,24?,25?,27?/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 69 mg/mL(200.4 mM). Water: 69 mg/mL(200.4 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Anna-Kaisa Koskinen, et al. Pharm Res. 2016 Jul;33(7):1752-68.
2. Anna-Kaisa Tuderman, et al. Int J Pharm. 2018 Mar 1;538(1-2):287-295.

Products are for research use only. Not for human use.