Fulacimstat (BAY1142524) is an orally available inhibitor of chymase with IC50 of 4 nM and 3 nM for human and hamster chymase enzyme, respectively.
CAS Number: 1488354-15-9
Molecular Weight: 487.38
Chemical Name: 1-(3-methyl-2-oxo-2, 3-dihydro-1, 3-benzoxazol-6-yl)- 2, 4-dioxo-3-[(1R)-4-(trifluoromethyl)-2, 3-dihydro-1H-inden- 1-yl]-1, 2, 3, 4-tetrahydropyrimidine-5-carboxylic acid
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO: 97 mg/mL(199.02 mM).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
- Friederike Kanefendt, et al. Clin Pharmacol Drug Dev. 2019 May;8(4):467-479.
- Hanna Tinel, et al. Circulation. November 14, 2017.Vol 136, Issue suppl_1.
Products are for research use only. Not for human use.
Payment & Security
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.