Catalog No. Size PriceQuantity
M7600-2 2mg solid $150
M7600-10 10mg solid $450


Fulacimstat (BAY1142524) is an orally available inhibitor of chymase with IC50 of 4 nM and 3 nM for human and hamster chymase enzyme, respectively.

Product information

CAS Number: 1488354-15-9

Molecular Weight: 487.38

Formula: C23H16F3N3O6




BAY 1142524

Chemical Name: 1-(3-methyl-2-oxo-2, 3-dihydro-1, 3-benzoxazol-6-yl)- 2, 4-dioxo-3-[(1R)-4-(trifluoromethyl)-2, 3-dihydro-1H-inden- 1-yl]-1, 2, 3, 4-tetrahydropyrimidine-5-carboxylic acid

Smiles: CN1C2=CC=C(C=C2OC1=O)N1C=C(C(O)=O)C(=O)N([C@@H]2CCC3C(=CC=CC=32)C(F)(F)F)C1=O


InChi: InChI=1S/C23H16F3N3O6/c1-27-17-7-5-11(9-18(17)35-22(27)34)28-10-14(20(31)32)19(30)29(21(28)33)16-8-6-12-13(16)3-2-4-15(12)23(24,25)26/h2-5,7,9-10,16H,6,8H2,1H3,(H,31,32)/t16-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 97 mg/mL(199.02 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Friederike Kanefendt, et al. Clin Pharmacol Drug Dev. 2019 May;8(4):467-479.
  2. Hanna Tinel, et al. Circulation. November 14, 2017.Vol 136, Issue suppl_1.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed